We are visionaries.
We believe that the enormous challenge of making cancer curable can be overcome only with a different approach.
Our approach is entirely empirical, we don’t take anything for granted. We re-define the challenge itself, and combine expertise from multiple disciplines into new methods and tools.
Nucleix is a liquid biopsy company revolutionizing cancer treatment with earlier disease detection, at a time when intervention can bring the greatest impact for patients. Leveraging PCR-based epigenetics, our pioneering testing approach uses methylation-based identification for early-stage and recurring cancer detection. Our non-invasive EpiCheck® platform delivers highly accurate and sensitive results, all while providing a seamless testing option for patients and the healthcare system. Our global team operates from San Diego, United States as well as from Rehovot Israel.
Chris Hibberd, B.Sc., MBA Executive Chairman & CEO
Chris Hibberd, B.Sc., MBA
A proven team builder with over 20 years of experience in working with innovative teams to identify, create and build high value medical device products and biotech discovery technologies. Co-Founded and built Astute Medical, an innovative medical technology discovery and diagnostic company. Built an impressive team, secured VC funding, negotiated debt financing, built a product pipeline, launched the 1st FDA cleared product for Acute Kidney Injury risk and negotiated numerous global collaborations. One of the collaborators, bioMérieux, acquired Astute Medical in April 2018. Prior to Biosite’s $1.7B acquisition in 2007, he led a productive business development and strategic planning group and co-founded Biosite Discovery to leverage a world class antibody capability. After securing an MBA from the University of Western Ontario in Canada, he worked for 5 years as a management consultant with the Boston Consulting Group in the US, Canada, Mexico and Spain. Graduated with a Chemical Engineering degree from the University of Toronto.
Todd Myers, B.Sc.Chief Financial Officer
Todd Myers, B.Sc.
Todd has over 25 years of experience in both public and private companies, primarily in the life science and healthcare fields. As the CFO of multiple companies, he has negotiated with investors and strategic partners to raise over $320 million in capital through the issuance of equity and debt, and the out-licensing of technology. Prior to joining Nucleix, Todd was the chief financial officer of Astute Medical, which was acquired in 2018 by bioMerieux, a multinational biotechnology company headquartered in France. While with Astute, he played a lead role in raising equity and debt capital to support the research, clinical/product development and commercialization of NephroCheck®, the first FDA cleared diagnostic for acute kidney injury, as well a lead role in Astute’s sales process. He was responsible for all finance and general and administrative activities at both Astute and its wholly-owned subsidiary in Europe. Prior to Astute, Todd was the chief financial officer at SGX Pharmaceuticals, a publicly-traded company focused on the discovery, development and commercialization of innovative cancer therapeutics, until its acquisition by Eli Lilly & Company. He was also the Director of Finance at CombiChem, Inc., a publicly-traded computational drug discovery company, which was acquired by DuPont Pharmaceuticals. Todd began his career as an auditor in the San Diego office of Ernst & Young and obtained a B.S. in accounting from the University of Illinois, Champaign-Urbana.
Michael G. VicariChief Commercial Officer
Michael G. Vicari
Over 30 years of healthcare experience, a culture influencer and team builder who has launched numerous innovations and built commercial organizations that have directly impacted patient care. Mike started his career in pharmaceuticals and quickly moved into senior leadership roles with such companies as Genentech (the world’s first biotech) and start-up companies like Monogram Biosciences, Inivata, Sequenom and Grail. Most recently as Senior Vice President of Sales at Grail, Mike built the commercial team that introduced the world’s first MCED (Multi-Cancer Early Detection) screening test, which reached $67 million in revenue in the first 18 months following launch. He also successfully scaled a commercial team for Sequenom that launched the world’s first NIPT (Non-Invasive Prenatal Test), which revolutionized genetic screening. Mike holds a BS in Organizational Behavior from the University of San Francisco.
Mathias Ehrich, M.DChief Scientific Officer
Mathias Ehrich, M.D
Mathias Ehrich, M.D., has more than 20 years of experience successfully developing, implementing and commercializing cutting-edge scientific technologies and clinical applications. Throughout his career, Dr. Ehrich has specialized in circulating cell-free DNA, epigenetics and oncology, and has launched more than 20 products across multiple categories, including instrumentation, reagents, clinical assay and collection devices. Previously, Dr. Ehrich co-founded Juno Diagnostics, where he built the foundational technology stack of in-home genetic testing devices, which led to the creation of four novel patent families. Additionally, as chief medical officer and chief scientific officer at Juno, Dr. Ehrich spearheaded clinical validation of the company’s low volume Non-Invasive Prenatal Screening (NIPS) method, led the successful development and launch of the first capillary blood collection device, and secured more than $28M in venture capital.
Eli Frydman, Ph.D, MBA President EMEA
Eli Frydman, Ph.D, MBA
With over 20 years industry experience, Eli is a seasoned healthcare executive with comprehensive management, operational and Board level experience, including start-up, multi-national, incubator and VC companies. Prior to joining Nucleix, Eli was Managing Director of Aurum Ventures, a healthcare-focused VC, serving on the Boards of its 10 portfolio companies, across different healthcare segments. Prior to Aurum, Eli served as CBO at FutuRx, a J&J, Takeda and Orbimed incubator, where he made key contribution to FutuRx set up and the establishment of multiple start-up companies; COO at Aposense (a drug development company; TASE: APOS), where he managed the company’s business development, operations and finance, led several big pharma agreements and played a key role in the company's TASE IPO; and Senior BD Manager at GE Healthcare Europe, leading multiple M&A transactions. Eli holds a Ph.D in Chemistry from the Weizmann Institute of Science and an MBA from the Ecole-Des-Ponts, Paris; he is also a member of 8400, Israel’s healthcare executives network, and of the EU Horizon Europe Jury committees in Brussels.
Ricardo A.J. ten Velden VP Sales & Marketing
Ricardo A.J. ten Velden
Ricardo has over 30 years of experience in business development and sales & marketing. He achieved a sustained record of success in the Life Sciences industry e.g. innovative (lifestyle) prescription drugs, generics, biologics, biosimilars, and medical devices. He started his career in Pharmaceuticals and later transitioned to molecular diagnostics. Before joining Nucleix he served as the Director Sales & Marketing EMEA of MDxHealth (ENX:MDXH), a multinational healthcare company that provides actionable genomic information to personalize the diagnosis and treatment of cancer. Prior to this he was commercial leader for international markets in companies such as Avery Dennison, Merck Sharp & Dohme and Organon (AkzoNobel). For Organon he worked more than six years as an expat in Italy. Back in the Netherlands he set up the Benelux subsidiary of Hikma Pharmaceuticals (LON:HIK). Ricardo studied law at VU University Amsterdam and marketing at the Netherlands Institute of Marketing.
Aharona Shuali, MD, MBA VP Medical
Aharona Shuali, MD, MBA
Aharona has over 10 years of experience in development and commercialization of oncology-targeted products in the pharmaceutical and medical device industries. Prior to Nucleix, Aharona served as Medical Manager at Roche Pharmaceutical Israel, Medical Director at AstraZeneca Israel, Senior Global Product Manager in Philips Healthcare and VP Oncology at Insightec. Aharona holds an MD from the Hebrew University, and an MBA from Tel Aviv University.
Danny Frumkin, PhDVP Research
Danny Frumkin, PhD
As co-founder of Nucleix, Danny brings extensive experience and know-how in molecular biology, cancer genetics, and DNA biochemistry. Alongside Adam, he co-developed a non-invasive high-resolution method for determination of cell lineage based on analysis of somatic DNA mutations, resulting in the establishment of an international lineage center at the Weizmann Institute. Danny is the author of 11 scientific papers and co-inventor of several patents. Danny holds an Ph.D. in Life Sciences from the Weizmann Institute, as well as an B.Sc. in Medical Sciences from Tel-Aviv University.
Adam Wasserstrom, PhDVP Software and Analytics
Adam Wasserstrom, PhD
Bringing deep knowledge in computer science, bioinformatics, and statistical analysis, Adam co-founded Nucleix and has been an instrumental part of building the company from its inception. Together with Danny, he co-developed a non-invasive high-resolution method for determination of cell lineage based on analysis of somatic DNA mutations, resulting in the establishment of an international lineage center at the Weizmann Institute. Adam is the author of 9 scientific papers and co-inventor of several patents. Adam holds a Ph.D. in Life Sciences from the Weizmann Institute, and a B.A in Computer Sciences cum laude and Music from Tel-Aviv University.
Eran Bram, PhD VP Product Development
Eran Bram, PhD
Eran is an experienced R&D manager with specific focus on the development and productization of In-vitro molecular diagnostics assays and software. Previously, Eran served as a Sr. Scientist and Manager at Asuragen Inc., and was the founder and CSO at Piercell Bio, Ltd. Eran is an author of 11 scientific papers, an inventor of 2 patents and has served as PI on multiple SBIR grants. Eran holds a PhD in Life Sciences from the Technion, Israel Institute of Technology and has completed his postdoctoral fellowship in biological engineering at MIT.
Radha Duttagupta, PhD VP Clinical Affairs
Radha Duttagupta, PhD
Dr. Radha Duttagupta brings over 10 years of experience in test development, trial strategy and pre- and post-market studies for LDT/RUO/IVD products in the clinical diagnostic industry. Prior to Nucleix, Radha served as Director of Clinical Operations and Clinical Development at Karius driving the clinical validity, utility and publication strategy for the Karius® Test (liquid biopsy for infectious diseases) in immunocompromised patients suspected with pneumonia. Radha has held previous positions at Cepheid (Danaher) leading clinical trials in the ID portfolio including Xpert® MTB/XDR (molecular DST for Extreme Drug Resistance TB) and Affymetrix (part of Thermofisher Scientific) in product and clinical development of pre and post-natal tests for copy number (CN) detection spanning CytoScan™ XON, CytoScan™ Optima and CytoScan™ Dx; the first-in-kind FDA and CE-marked blood test to aid in the diagnosis of developmental delay/intellectual disabilities, congenital anomalies, and/or dysmorphic features. Radha has a Ph.D in Biochemistry and Molecular Genetics from Rutgers University and University of Medicine and Dentistry of New Jersey (UMDNJ), Robert Wood Johnson Medical School, New Jersey and was a post-doctoral fellow in the Transcriptome group at Affymetrix.
OrbiMed Israel Limited Partnership
OrbiMed Israel Limited Partnership
OrbiMed have been investing globally for over 20 years across the healthcare industry: from early-stage private companies to large multinational corporations. Investments are made in one of three strategies: public equity, private equity, and royalty opportunities. Their team of over 80 distinguished scientific, medical, investment and other professionals manages over $13 billion across public and private company investments worldwide.
Zohar Zisapel
Zohar Zisapel
Zohar Zisapel is a successful Israeli entrepreneur in Israel’s advanced high-tech industry.
Aurum Ventures M.K.I. Ltd
Aurum Ventures M.K.I. Ltd
Aurum Ventures MKI provides value added growth capital to exceptional entrepreneurs in the healthcare area. While we focus on investing in unique, cutting edge technologies that will mature into successful business companies, our investments reflect our own values, so we prefer investing in companies that, through their sound commercial propositions, also contribute to the well-being of mankind. Our team is comprised of senior and experienced hands-on executives who work actively with the portfolio companies in enhancing their strategic and execution capabilities. We typically take a long-term approach, understanding that ventures in the life sciences and healthcare areas take time to mature and be successful.
RA Capital Management
RA Capital Management
RA Capital Management, LP is a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare and life science companies that are developing drugs, medical devices, diagnostics, services and research tools. The flexibility of its strategy allows RA Capital to provide seed funding to startups and to lead private, IPO, and follow-on financings for its portfolio companies, enabling management teams to drive value creation from inception through commercialization. At RA Capital’s core is its TechAtlas research division, a scientifically trained team that maps out competitive landscapes to put data into context, identify breakthroughs, and originate conviction in new ideas. TechAtlas provides market intelligence, technical diligence, and other resources to RA Capital's internal Investment team as well as its portfolio companies.
Sands Capital
Sands Capital
Sands Capital is an active, long-term investor in leading innovative businesses globally. Our approach combines analytical rigor and creative thinking to identify high-quality growth businesses that are creating the future. Through an integrated investment platform spanning venture capital, growth equity and public equity, we provide growth capital solutions to institutions and fund sponsors in more than 40 countries. An independent, staff-owned firm founded in 1992 with offices in the Washington, D.C. area and Singapore, Sands Capital managed more than USD $80 billion in client assets as of September 30, 2021.
Chris Hibberd, Executive Chairman & CEO
Chris Hibberd, Executive Chairman & CEO
A proven team builder with over 20 years of experience in working with innovative teams to identify, create and build high value medical device products and biotech discovery technologies. Co-Founded and built Astute Medical, an innovative medical technology discovery and diagnostic company. Built an impressive team, secured VC funding, negotiated debt financing, built a product pipeline, launched the 1st FDA cleared product for Acute Kidney Injury risk and negotiated numerous global collaborations. One of the collaborators, bioMérieux, acquired Astute Medical in April 2018. Prior to Biosite’s $1.7B acquisition in 2007, he led a productive business development and strategic planning group and co-founded Biosite Discovery to leverage a world class antibody capability. After securing an MBA from the University of Western Ontario in Canada, he worked for 5 years as a management consultant with the Boston Consulting Group in the US, Canada, Mexico and Spain. Graduated with a Chemical Engineering degree from the University of Toronto.
Dr. Heiner Dreismann
Dr. Heiner Dreismann
Dr. Dreismann, is a seasoned executive with more than 30 years of experience in the health care industry, and is regarded as a pioneer in the early adoption of the polymerase chain reaction (PCR) technique, one of the most ubiquitous technologies in molecular biology and genetics research today. He had a successful career at the Roche Group from 1985 to 2006 where he held several senior positions, including President and CEO, Roche Molecular Systems, Head of Global Business Development, Roche Diagnostics and Member of Roche’s Global Diagnostic Executive Committee. Dr. Dreismann currently serves on the boards of several public and private health care companies. He earned a master of science degree in biology and his doctor of philosophy degree in microbiology/molecular biology (summa cum laude) from Westfaelische Wilhelms University (The University of Munster) in Germany.
Erez Chimovits
Erez Chimovits
Erez Chimovits is a Partner at OrbiMed. Erez has 14 years of operational experience, including 10 years of senior managerial experience in public companies. Prior to joining OrbiMed Erez was the CEO of NasVax (TASE:NSVX). NasVax acquired Protea and struck agreements with GlaxoSmithKline and Novartis. Previously, Erez spent more than seven years with Compugen (Nasdaq:CGEN), as President, Compugen USA Inc. and Executive VP, Commercial Operations. At Compugen, he had responsibility for more than 100 people and led multiple transactions including J&J, Novartis, Teva, Abbott, Medarex and others. Erez earned his M.B.A., M.Sc. in Microbiology and his B.Sc. from Tel Aviv University.
Dr. Thomas Buchholz
Dr. Thomas Buchholz
Dr. Buchholz is a corporate SVP and Medical Director of Scripps MD Anderson Cancer Center in San Diego. His responsibilities include oversight of the clinical care of cancer patients, the development of clinical and translational research activities, and academic collaborations with MD Anderson. He also continues a radiation oncology practice focused on breast cancer. He previously has held a variety of clinical, research, academic and administrative leadership positions with MD Anderson Cancer Center in Houston, including division head and department chair of radiation oncology, Provost ad-interim, and Executive Vice President/Physician-in-Chief, during which he was responsible for all aspects of clinical care and operations of MD Anderson’s hospital and ambulatory clinics. Nationally he has held a variety of leadership roles including two terms as co-chair of the NCI's Breast Cancer Steering Committee. His academic efforts and efforts to improve the patient experience have been recognized with several national awards. Dr. Buchholz earned his medical degree from Tufts University School of Medicine in Boston. He completed his residency and a radiobiology research fellowship at the University of Washington Medical Center in Seattle. He is board certified by the American Board of Radiology and the National Board of Medical Examiners. He earned his bachelor’s degree in philosophy from Bucknell University in Lewisburg, Pa, and currently serves on Bucknell's Board of Trustees.
Ilan Lior
Ilan Lior
Ilan Lior serves as the general counsel of Aurum Ventures M.K.I. Ltd. and is member of Aurum’s senior management team. He also serves on various boards of Aurum’s portfolio companies. Prior to joining Aurum, Ilan was a partner in a boutique law firm where he headed the corporate and commercial practice group. Ilan is a member of the Israeli bar and holds LLW and a BA (eco), both from the Tel Aviv University.
Nate Davis
Nate Davis
Nate Davis is an Analyst on the Investment Team at RA Capital Management. Nate conducts due diligence on biotechnology companies at RA Capital and serves as a Board Director for The Covid Apollo Project and Nucleix. Previously, Nate worked closely with the Investment Team, as a Senior Associate within the TechAtlas division, to originate conviction in potential investments by identifying breakthroughs and putting data into context. Prior to RA Capital, Nate worked as an Investment Analyst at Wolfram Ventures. Nate has a BS in Biological Sciences from University of Vermont.
Parker Cassidy
Parker Cassidy
Parker Cassidy is a Partner at Sands Capital and focuses on the firm’s diagnostic investments. He has a BS in Mechanical Engineering from Boston University and an MBA from Darden Graduate School of Business Administration from the University of Virginia. Prior to Sands Capital, Parker was a Principal on the investment team at RA Capital Management. Parker also worked at Farcast Biosciences where he served as the Chief Commercial Officer and as the Head of Strategy and Business Development. Prior to Farcast Biosciences, Parker held various leadership roles of increasing responsibility at both Becton Dickinson and Serologicals.”
Prof. Fred Witjes
Prof. Fred Witjes
Prof. Fred Witjes is professor in oncological urology. His research interest is translational and clinical research in bladder, prostate and testicular cancer. He has many training and teaching activities. He is a member of several international societies, and he chairs, amongst others, the Dutch guidelines committee on bladder cancer and the EAU guidelines committee on metastatic and muscle-invasive bladder cancer. He is reviewer for many, and editor of several urological and oncological journals. He is involved in and leads many studies and projects which has resulted in many lectures and over 550 (peer reviewed) publications, reviews and bookchapters.
Dr. Barton Grossman
Dr. Barton Grossman
Part-time Professor in the Dept. of Urology M.D. Anderson Cancer Center. Dr. Grossman was awarded his medical degree from Temple University. He then completed a residency in Urology at the University of Michigan. He obtained additional training in a clinical and research fellowship at Memorial Sloan-Kettering Cancer Center and returned to the University of Michigan where he rose to Professor. In 1994, he joined the faculty of The University of Texas M. D. Anderson Cancer Center where he is Professor and Deputy Chairman of the Department of Urology. Dr. Grossman has numerous publications and continues to have an active research laboratory.
Prof. Yair Lotan
Prof. Yair Lotan
Yair Lotan, MD, is a professor of urology, chief of urologic oncology, and holder of the Jane and John Justin Distinguished Chair in Urology, in Honor of Claus G. Roehrborn, MD at UT Southwestern Medical Center in Dallas, Texas. He also serves as Vice Chair of Clinical Affairs of the Department of Urology and Head of the Clinical Research office. He is the medical director of the urology clinic at Parkland Health and Hospital System. Dr. Lotan graduated from the University of Texas at Austin and earned his MD from Baylor College of Medicine in Houston. Dr. Lotan is known for his research on urine markers and molecular markers that help detect cancer and to determine which patients are at higher risk for recurrent cancer. He is also interested in health economics research, which evaluates the cost-effectiveness of surgery and cancer prevention. Dr. Lotan has published over 600 peer reviewed articles, review papers and book chapters. He is also an editorial reviewer for many medical periodicals, including the Journal of Urology, European Urology, Cancer, Urologic Oncology, and the British Journal of Urology International. Dr. Lotan currently holds a position as co-chair of the Harold C. Simmons Comprehensive Cancer Center disease-oriented team, focused on urologic cancers. He is a member of UT Southwestern’s Clinical Research Planning Group and the Tissue Bank Steering Committee and Cancer Committee. Dr. Lotan is a popular guest speaker at medical conferences around the world and belongs to numerous professional organizations, including the American Urological Association, the Society of Urologic Oncology, and the Bladder Cancer Advocacy Network.
Prof. Paolo Gontero
Prof. Paolo Gontero
Paolo Gontero holds the position of Full Professor of Urology at the University of Torino School of Medicine and since 2016 has been appointed as Chairman of the Division of Urology, San Giovanni Battista Hospital (Molinette), Torino, Italy. His main clinical interests are in the field of Surgical Uro-Oncology, devoted to Robotic and Laparoscopic oncological surgery of prostate, kidney and bladder cancers. He has expertize in minimally invasive live donor nephrectomy and reconstructive surgery of transplanted kidney. He has authored and co-authored more than 450 publications on international journals with his main research interests pertaining the development of new treatment modalities for non-muscle invasive bladder cancer and prostate cancer. He is involved in international trials and working groups on the development of new diagnostic and therapeutic modalities for prostate and bladder cancer. He is currently chair of the European Guidelines for non-muscle invasive bladder and holds membership of the IBCN. He is also member of the Journal of Urology Editorial Board.
Prof.Param Mariappan
Prof.Param Mariappan
Professor Param Mariappan MBBS(Hons), FRCS(Urol), PhD, FEBU, CBU(Mal) has been a Consultant Urological Surgeon in Edinburgh for over 18 years, with a practice that is almost exclusively Bladder Cancer. Having performed over 800 cystectomies and several thousand TURBTs, he has one of the UKs largest contemporary series and leads the Bladder Cancer surgical service in Edinburgh with a focus on effectiveness and efficiency in patient-centred care. Prof Mariappan plays a leading role in the development and continuation of the Scottish QPI programme for Bladder Cancer and designed the Scot BC Quality OPS project. He has published widely, featuring in some seminal work. He sits on the EAU guideline panels for Bladder Cancer and UTUC, and is a core committee member of The International Bladder Cancer Group (IBCG). Outside work, Param is a keen 6 handicap golfer.
Dr. Peter Mazzone
Dr. Peter Mazzone
Dr. Peter Mazzone is a pulmonologist at the Cleveland Clinic where he directs the Lung Cancer Program for the Respiratory Institute and the Lung Cancer Screening Program for the hospital system. His clinical interests include prevention, screening, nodule management, lung cancer diagnosis, staging, and characterization. He has research interests in each of these clinical areas, including work on the development of molecular biomarkers for lung cancer detection. He has served in leadership positions within Chest and the American Thoracic Society which have allowed him to lead policy development projects related to quality metrics for the evaluation of lung cancer, components necessary for high-quality lung cancer screening, and the clinical application of molecular biomarkers for lung cancer detection. He has also been an active member of evidence-based guidelines related to lung cancer screening and lung nodule management.
Dr. Gerard A. Silvestri
Dr. Gerard A. Silvestri
Dr. Gerard Silvestri is the Hillenbrand Professor of Thoracic Oncology at the Medical University of South Carolina. He completed his training in Pulmonary and Critical Care Medicine and received an additional degree in health services research, both at Dartmouth. He is widely regarded as an international expert in lung cancer. His research includes screening for lung cancer, lung nodule evaluation, diagnosis and staging of lung cancer, development of biomarkers for disease risk and treatment, and disparities in delivering lung cancer care to underserved communities. Dr. Silvestri is a writer and editor of the American College of Chest Physicians lung cancer guidelines. He has authored more than 280 scientific articles, book chapters and editorials. He has served on multiple editorial boards and currently serves on the editorial board of the journal Chest. Dr. Silvestri is past president of the American College of Chest Physicians (CHEST), a society serving 20,000 chest physicians worldwide. He currently serves on the steering committee of the American Cancer Society’s National Lung Cancer Roundtable. Dr. Silvestri was the recipient of the 2020 lifetime achievement award in Lung Cancer from the American Thoracic Society. In 2022, Dr. Silvestri was named a Master Fellow of the American College of Chest Physicians, a distinction awarded to only 40 members in the nearly 90 years of that organization’s existence.
Prof. Martin C. Tammemägi
Prof. Martin C. Tammemägi
Prof. Martin Tammemägi has MSc and PhD degrees in Epidemiology from the University of Toronto. He served as co-investigator in the US NIH NCI sponsored National Lung Screening Trial. Currently, he is Professor of Epidemiology in the Department of Health Sciences at Brock University in Canada and is Scientific Lead on Cancer Care Ontario’s Lung Cancer Screening Pilot for People at High Risk. His research has a focus on lung cancer screening, lung cancer risk prediction modelling and prediction modelling of which pulmonary nodules detected on computed tomography screening are cancer. His lung cancer risk prediction models, including the PLCOm2012 (Tammemagi MC et al. NEJM 2013) and his nodule malignancy probability model (PanCan model; McWilliams A, Tammemagi M, et al. NEJM 2013) have received widespread validation and implementation. Regarding programmatic public health implementation of lung cancer screening, he has a strong research and applied interest in indicators and measures of screening performance through the different phases of lung cancer screening programs.
Prof. Mina Gaga
Prof. Mina Gaga
Dr. Mina Gaga MD, PhD is Director of the 7th Respiratory Medicine Dept and Asthma Centre at Athens Chest Hospital "Sotiria". The hospital is a center of excellence for lung disease, catering to more than 50000 inpatient and 100000 outpatient and emergency patient visits. Among those, more than 2000 new lung cancer patients are diagnosed, staged and treated per year. Dr Gaga is much involved in clinical work, focusing particularly in lung cancer and asthma, in clinical research and in medical education programs. She has been actively involved as PI in multiple clinical trials, has been active internationally in guideline development for screening in lung cancer and severe asthma and has published extensively in these research areas. She has moreover served as Director of Learning Resources of the ERS School, Secretary of the European Board of Accreditation in Pneumology (EBAP), Secretary General and president of the ERS, serves in the HERMES examination committee and the European Αdult and Thoracic Oncology HERMES Diplomas.
Prof. John Field
Prof. John Field
Prof. John Field, PhD, FRCPath has a Personal Clinical Chair in Molecular Oncology at the University of Liverpool. He is a Visiting Professor at University College London, holds the post of Director of Research of the Roy Castle Lung Cancer Research Programme. He is the Chief Investigator for the UK Lung Cancer Screening Trial (UKLS). Previous Chair of the IASLC Screening Prevention & Early Detection Committee and he formed IASLC Strategic Screening Advisory Group. Member of the ILCCO Steering Committee He was presented with the IASLC Joseph Cullen Award at the WCLC 2011, in recognition of lifetime scientific achievements in lung cancer prevention research. He is Chair of the IASLC Strategic Screening Advisory Committee. He is the principle investigator of the Liverpool Lung Project, a molecular- epidemiological study into the early detection of lung cancer (~12,000 recruited), funded by the Roy Castle Lung Cancer Foundation. The UKLS and the LLP form part of the NCRI Lung Cancer portfolio. He is also a Partner in the FP7 CURELUNG and LCAOS projects and the NIH GWAS non-smokers and the Oncoarray studies. He is also heavily involved in the identification of molecular diagnostic markers in lung and head & neck cancers. His research funding has been provided mainly by the RCF, NWCRF, MRC, CRUK, EU, NIH and the HTA. Professor Field is the author of over 270 international (peer reviewed) papers in his area of expertise and has given more than 350 presentations at medical and scientific conferences around the world.
Israel Innovation Authority
Israel Innovation Authority
The Office of the Chief Scientist was established in 1974. It was renamed the Israel Innovation Authority in 2016. The main aim of the department is to increase economic empowerment within the civilian sector of the Israeli economy. Main activities include the funding of research and policy-making within its sphere of influence. The development and prominence of the OCS was further strengthened by the development of the Venture Capital industry within Israel in the 1990s. A variety of ongoing support programs offered by the Authority provide financial and developmental resources to entrepreneurs and companies of all sizes and stages performing industrial R&D research within Israel.
HORIZON 2020
HORIZON 2020
Horizon 2020 is the biggest EU Research and Innovation programme ever with nearly €80 billion of funding available over 7 years (2014 to 2020) in addition to the private investment that this money will attract. It promises more breakthroughs, discoveries and world-firsts by taking great ideas from the lab to the market. Horizon 2020 is the financial instrument implementing the Innovation Union, a Europe 2020 flagship initiative aimed at securing Europe's global competitiveness. Seen as a means to drive economic growth and create jobs, Horizon 2020 has the political backing of Europe’s leaders and the Members of the European Parliament. They agreed that research is an investment in our future and so put it at the heart of the EU’s blueprint for smart, sustainable and inclusive growth and jobs. By coupling research and innovation, Horizon 2020 is helping to achieve this with its emphasis on excellent science, industrial leadership and tackling societal challenges. The goal is to ensure Europe produces world-class science, removes barriers to innovation and makes it easier for the public and private sectors to work together in delivering innovation.
The (CTA) Clinical Trial Assistant, will be working closely with the clinical team to ensure the efficient and effective conduct of clinical studies. Assist the clinical team with the preparation, handling, distribution, filing, and archiving of clinical documentation, supplies, samples and reports according to the standard operating procedures, and maintenance of tracking information.
Responsibilities:
• Provide general administrative support to the Clinical Department.
• Assist the Clinical team in completion of all required tasks to meet departmental and
project goals.
• Support the Clinical team with study start-up and ongoing conduct of studies.
• Assist project team with study specific documentation and guidelines.
• Set up, organize and maintain clinical study documentation (e.g. Investigator site file, eTMF,
CRFs, etc.) including preparation for internal/external audits, review and reconciliation.
• Process Data Collection Forms i.e. log in, tracking and quality control for the study.
• Coordinate ordering/distribution and tracking of trial materials (e.g. lab supplies, forms
etc.).
• Coordinate and track shipments of trial samples.
• Support project team with trial progress tracking by updating the relevant study systems.
• Assist in coordination and tracking of site payments and other study related
budget/invoices, as applicable (e.g. CRO, vendors and central lab).
• Participate and interact with clinical sites and vendors such as: CRO and Central labs.
• To be familiar with ICH GCP, appropriate regulations, relevant company’s SOP’s and internal
systems.
• To be familiar with the roles of the Clinical Research Associates (CRA) including site visits.
• Contact clinical sites to obtain study documents (e.g., enrollment logs, missing forms, etc.).
• Coordinate translations.
• Assist the project team with coordinating and preparing meetings and generate meeting
minutes.
• Assist in the generation of slide presentations, tracking spreadsheets etc.
• Support Clinical department activities with other tasks as may be needed, from time to
time.
Requirements:
• BA/BSc (or equivalent) in one of the life sciences or health care - required.
• GCP and/or CRA certificate – an advantage.
• Research or health care related work experience - preferred.
• Study coordination or research assistance experience or prior Clinical Research Organization (CRO) experience - preferred.
• Computer skills including working knowledge of Microsoft Word, Excel, PowerPoint and Outlook - required.
• Administrative support experience - an advantage.
• Excellent organizational skills, ability to manage multiple tasks and attention to detail.
• Excellent written and verbal communication skills - must be fluent in both English and Hebrew.
• Effective time management and organizational skills.
• Ability to establish and maintain effective working relationships with coworkers, managers, sites and vendors.
• Willingness to travel for job related activities if required.
This position is based at our Israeli headquarters, located in Rehovot.
We encourage you to express your interest in this opportunity by sending your responses directly to us. Please send your application or reactions to: Jobs@Nucleix.com. We look forward to hearing from you!
As Director of Medical Affairs USA, you will shape clinical evidence and expert advocacy that establish our assays as the standard of care, building relationships with key opinion leaders (KOLs) and leading our evidence generation and commercial team partnership.
What You’ll Do
As a key early hire you will:
• Partner for commercial success. Work cross-functionally with Customer Success and Market Access to secure adoption, reimbursement and strategic partnerships
• Build and nurture thought-leadership. Create a nationwide KOL strategy and cultivate lasting relationships that drive evidence generation and guideline adoption
• Own evidence generation. Design post-marketing study plans, publication roadmaps and educational programs that highlight the clinical value of Nucleix diagnostics
• Champion scientific communication. Ensure all materials from slide decks, manuscripts to field-team resources are medically rigorous and compliant with
regulatory standards.
• Lead and mentor. Guide team members and collaborate with Commercial, Clinical, Regulatory and external investigators
• Connect. Engage the field and scientific community with approximately 25 % travel
What We’re Looking For
• Pharm.D., Ph.D., M.D. or Master’s with equivalent experience
• 8 years in biotech, pharma or diagnostics, including clinical product launch experience
• Deep clinical-scientific acumen in oncology or relevant specialties; comfortable interpreting complex data
• Demonstrated ability to lead independently, including setting priorities and making sound decisions to move the function forward
• Comfortable working in a binational environment and reporting structureProven success influencing cross-functional teams and external stakeholders
• Outstanding written, verbal and presentation skills for high-level scientific audiences
• Demonstrated ability to design studies, manage and execute multiple projects and lead or mentor teams in a dynamic, fast-changing setting
Preferred Skills
• Prior leadership of national medical affairs programs
• Experience shaping clinical guidelines
What We Offer
• A mission-driven and collaborative environment with opportunities to work with a talented team and interact directly with executive leadership
• Opportunity to build and lead a best-in-class Medical Affairs function
• Competitive compensation, equity, and 100% paid health benefits
• Flexible, remote work schedule
• The chance to be part of a company that's transforming cancer detection
Ready to Join Us?
If you’re a Medical Affairs leader who thrives on scientific rigor, strategic partnership and life-changing impact, we’d like to meet you. Apply today talent@nucleix.com and help us redefine what is possible in early cancer detection.
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